This medicine, among other things, inhibits the adhesion and clumping of platelets and thus prevents the formation of blood clots (thrombi) (inhibition of platelet aggregation). It is used
For unstable angina (heart pain caused by poor circulation in the coronary arteries) – in addition to standard therapy
For acute myocardial infarction – as part of standard therapy,
To prevent a second infarction after the first infarction (for the prevention of a second infarction),
After operations or other interventions on arterial blood vessels (after arterial surgery or interventional procedures, such as coronary artery bypass grafting [CABG], percutaneous transluminal coronary angioplasty [PTCA]),
To prevent a temporary decrease in blood flow to the brain (TIA: transient ischemic attacks) and brain infarctions after the onset of previous stages (for example, temporary paralysis of the muscles of the face or arms or temporary loss of vision).
Active ingredients – 100 mg acetylsalicylic acid
Excipients
Silicon dioxide, highly dispersed, Microcrystalline cellulose, Methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30%, triacetin, sodium dodecyl sulfate, potato starch, 60 mg lactose-1-water, Polysorbate 80, talc.
Dosage:
Recommended dose:
Unless otherwise prescribed by a doctor, the usual dose is:
For unstable angina (heart pain due to circulatory disorders in the coronary arteries)
The recommended daily dose is 1 gastro-resistant tablet (equivalent to 100 mg acetylsalicylic acid per day).
In acute heart attack
The recommended daily dose is 1 gastro-resistant tablet (equivalent to 100 mg acetylsalicylic acid per day).
To prevent a second heart attack after a first heart attack (recurrent heart attack prophylaxis)
The recommended daily dose is 3 gastro-resistant tablets (equivalent to 300 mg acetylsalicylic acid per day).
After surgery or other interventions on arterial blood vessels (after surgical or interventional procedures on arterial vessels; eg after ACVB; after PTCA)
The recommended daily dose is 1 gastro-resistant tablet (equivalent to 100 mg acetylsalicylic acid per day).
The most optimal time to start treatment with this drug after coronary artery bypass grafting (CABG) is 24 hours after the operation.
For the prevention of transient cerebral infarction (TIA) and cerebral infarction after the onset of previous stages
The recommended daily dose is 1 gastro-resistant tablet (equivalent to 100 mg of acetylsalicylic acid per day).
This drug is intended for long-term use.
Side effects
Gastrointestinal complaints such as heartburn, nausea, vomiting, abdominal pain and diarrhea.
Minor blood loss from the gastrointestinal tract (microbleeding), gastric or intestinal bleeding. With prolonged use, anemia (iron deficiency anemia) may occur due to hidden blood loss from the stomach or intestines. Ulcers of the stomach or intestines, which in very rare cases can lead to perforation, gastrointestinal inflammation.
Skin reactions (very rarely up to severe febrile skin rash with mucosal lesions (erythema multiforme exudative)).
Hypersensitivity reactions of the skin, respiratory tract, gastrointestinal tract and cardiovascular system, especially in asthmatics.
Signs of overdose may include headaches, dizziness, confusion, hearing loss or ringing in the ears (tinnitus).
Accelerated breakdown or death of red blood cells and a certain form of anemia in patients with severe glucose-6-phosphate dehydrogenase deficiency.
Bleeding, such as For example, nosebleeds, bleeding gums, skin bleeding or bleeding from the urinary tract and genitals with possible prolongation of bleeding time. This effect may last from 4 to 8 days after administration.
Impaired renal function and acute renal failure.
Low blood sugar (hypoglycemia).
Low doses of acetylsalicylic acid reduce the excretion of uric acid. In patients at risk, this may trigger an attack of gout.
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, talk to your doctor or pharmacist before taking this medicine.
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