PRENACAPS FOLATE contains 800 mcg of the bioactive form of folic acid (Quatrefolic®) with proven bioavailability. 800 mcg Quatrefolic® Quatrefolic® is an active form of folic acid with high bioavailability in studies (tests can be found at the bottom of this page). Pullulan Pullulan vegetable capsules are produced by fermentation. This capsule is suitable for vegetarians and vegans. Transparent composition in glass packaging The product does not contain, among other things, artificial fillers, preservatives, sweeteners. COMPOSITION OF THE PRODUCT The recommended daily dose (1 capsule) contains (reference dose of consumption%): Folian (Quatrefolic) – 800 mcg (400%), inulin – 345 mg. Ingredients: inulin (chicory root), pullulan (capsule shell), folic acid (glucosamine salt (6S)-5-methyltetrahydrofolic acid). SUGGESTED USE Take 1 capsule once daily with food Net weight: 20.7 g. Capsules/servings: 60/60. Storage conditions: Protect from light, store at room temperature, in a dry place out of the reach of children. PRECAUTIONS The product should be used after consulting a physician. Do not exceed the recommended daily dose for consumption throughout the day. The product should not be used as a substitute for a varied diet. Do not use if you are allergic to any of the ingredients. A balanced diet and a healthy lifestyle are the basis for the proper functioning of the body. ACTIONS AND RESEARCH RESULTS Importance of Folic Acid during Pregnancy and Breastfeeding Folic acid is one of the most important compounds for the developing baby in the abdomen. Deficiency of this nutrient in the mother is one of the reasons for the development of, among other things, defects in the child’s nervous system. Folic acid is also important for the health of the expectant mother and breastfeeding mother. It helps in proper blood production and maintaining proper homocysteine metabolism. In addition, it supports the functioning of the immune system and helps reduce fatigue and fatigue. The optimal dose should be selected with a gynecologist. The Polish Gynecological Society recommends: – women from the low risk group – 400 mcg / day (12 weeks before trying to conceive a child – pregnancy – breastfeeding) – women from the medium risk group (for example, smoking cigarettes), alcohol consumption, certain diseases, certain medications, reduced MTHFR activity) – 800 mcg / day (12 weeks before trying to conceive – pregnancy – breastfeeding) – in high-risk women – higher consumption. ———– ACTIVE FOLIC ACID For use by the body, folic acid must be converted to its active form after ingestion. According to available data, on average, every second person in Europe has an impairment in the process of converting folic acid to its active form. Quatrefolic® is an active form that does not require transformation and can be used by the body immediately. TEST RESULTS Quatrefolic® Study 1 The study involved groups receiving the same doses of Quatrefolic® and folic acid, respectively. after administration compared to folic acid (diagram 1) • Quatrefolic® achieved more than 9 times higher total bioavailability of the active substance (AUC8h ng/ml h ) compared to folic acid (fig. 2). Study 2 This study compared the bioavailability of Quatrefolic® with calcium L-methylfolate. High bioavailability of both forms is shown. However, in the case of the drug Quatrefolic®, the maximum concentration of the active substance after administration (Cmax, nmol / l) was 10% higher than that of calcium L-methylfolate. Source: Yarosh M., Nutritional norms for the population of Poland, 2017, Institute of Food and Nutrition; Recommendations of the Polish Gynecological Society on the use of vitamins and trace elements in pregnant and lactating women planning a pregnancy, Ginekol Pol. 5/2014, 85, 395-399;
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