“Composition
Active substance per suppository: Glycerol 1375 mg
Excipients: sodium stearate, sodium bicarbonate.
Directions
Suppositories Glycerol 1375 mg for children are indicated for short-term treatment of periodic constipation.
Glycerol is a compound widely used in the pharmaceutical industry due to its lubricating, osmotic, softening and moisturizing properties.
It stimulates peristalsis both due to the irritating effect exerted directly on the cells of the intestinal mucosa and due to the dehydration it causes in the mucosa itself. It can stimulate contractions of the rectum.
Method of administration and dosage
The correct dose is the minimum sufficient dose to ensure easy evacuation.
It is recommended to initially use the minimum indicated doses.
Adults and adolescents (12-18 years): 1 adult suppository as needed, maximum 1 or 2 times daily.
Children 2 to 11 years: 1 children’s suppository as needed, maximum 1 or 2 times daily.
Directions for use
Remove suppository from package and moisten if necessary to facilitate rectal insertion.
If suppositories have softened, immerse containers in cold water before opening.
Children under twelve years of age should only use the drug after consultation with a doctor.
Laxatives should be used as infrequently as possible and for no more than seven days.
A diet rich in liquids enhances the effect of the drug.
Warnings
Laxatives should be used as infrequently as possible and for no more than seven days.
For longer use, a doctor’s prescription is required after adequate assessment of the individual case.
Treatment of chronic or recurrent constipation always requires medical intervention for diagnosis, prescription of medication and monitoring during therapy. Elderly or unhealthy individuals should also consult a physician before using the drug.
Abuse of laxatives can cause persistent diarrhea, leading to loss of water, mineral salts (especially potassium) and other essential nutrients. In the most severe cases of abuse, dehydration or hypokalemia may occur, which may lead to cardiac or neuromuscular dysfunction, especially in the case of concomitant treatment with cardiac glycosides, diuretics or cortico.
Abuse of laxatives, especially contact (stimulant) laxatives, can cause dependence (and therefore the possible need for gradual dosage increases), chronic constipation and loss of normal bowel function (intestinal atony).
In case of constipation, it is recommended to first adjust dietary habits by including sufficient fiber and water in the daily diet.
When taking laxatives, it is recommended to drink at least 6-8 glasses of water or other liquids per day to help soften the stool.
Contraindications
Hypersensitivity to the active substance or any of the excipients.
Acute or unknown abdominal pain
Nausea or vomiting
Intestinal obstruction or stenosis
Rectal bleeding of unknown origin
Acute hemorrhoidal crisis with pain and bleeding
Severe dehydration.”
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